A groundbreaking study published today reveals that hydrogen-rich water supplementation may offer significant benefits for patients suffering from chronic high-altitude disease (CHAD). In a rigorously designed double-blind, randomized controlled trial, researchers found that daily intake of hydrogen-rich water led to:
A clear reduction in blood markers of oxidative stress.
Decreased levels of key inflammatory mediators associated with high-altitude physiological stress.
Modulation of hub genes tied to inflammation and immune cell migration, including neutrophil chemotaxis.
These findings align with a growing body of research supporting molecular hydrogen as a selective antioxidant that neutralizes harmful radicals (like •OH and ONOO–) without disrupting healthy cellular signaling. While much of the prior evidence came from animal models or other clinical contexts (e.g., liver disease, ulcerative colitis), this is the first clinical confirmation in individuals living at high altitude.
Though promising, the authors call for larger, longer-term trials to fully understand the therapeutic potential and clinical applicability of hydrogen-rich water for CHAD.
https://www.sciencedirect.com/science/article/abs/pii/S0963996925014565
Research provided by Science Direct.
